Tonicity-responsive enhancer binding protein haplodeficiency attenuates seizure severity and NF-κB-mediated neuroinflammation in kainic acid-induced seizures

Kainic acid (KA)-induced seizures followed by neuronal death are associated with neuroinflammation and blood–brain barrier (BBB) leakage. Tonicity-responsive enhancer binding protein (TonEBP) is known as a transcriptional factor activating osmoprotective genes, and in brain, it is expressed in neuro...

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Bibliographische Detailangaben
Hauptverfasser: Shin, H J, Kim, H, Heo, R W, Kim, H J, Choi, W S, Kwon, H M, Roh, G S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207478/
https://ncbi.nlm.nih.gov/pubmed/24608792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.29
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