β-Cell Function, Incretin Effect, and Incretin Hormones in Obese Youth Along the Span of Glucose Tolerance From Normal to Prediabetes to Type 2 Diabetes

Using the hyperglycemic and euglycemic clamp, we demonstrated impaired β-cell function in obese youth with increasing dysglycemia. Herein we describe oral glucose tolerance test (OGTT)-modeled β-cell function and incretin effect in obese adolescents spanning the range of glucose tolerance. β-Cell fu...

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Hauptverfasser: Michaliszyn, Sara F., Mari, Andrea, Lee, SoJung, Bacha, Fida, Tfayli, Hala, Farchoukh, Lama, Ferrannini, Ele, Arslanian, Silva
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2014
Schlagworte:
Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207396/
https://ncbi.nlm.nih.gov/pubmed/24947360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1951
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