Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes

Studies in type 1 diabetes indicate potential disease heterogeneity, notably in the rate of β-cell loss, responsiveness to immunotherapies, and, in limited studies, islet pathology. We sought evidence for different immunological phenotypes using two approaches. First, we defined blood autoimmune res...

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Autori principali: Arif, Sefina, Leete, Pia, Nguyen, Vy, Marks, Katherine, Nor, Nurhanani Mohamed, Estorninho, Megan, Kronenberg-Versteeg, Deborah, Bingley, Polly J., Todd, John A., Guy, Catherine, Dunger, David B., Powrie, Jake, Willcox, Abby, Foulis, Alan K., Richardson, Sarah J., de Rinaldis, Emanuele, Morgan, Noel G., Lorenc, Anna, Peakman, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2014
Soggetti:
Immunology and Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207393/
https://ncbi.nlm.nih.gov/pubmed/24939426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0365
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