Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes

Studies in type 1 diabetes indicate potential disease heterogeneity, notably in the rate of β-cell loss, responsiveness to immunotherapies, and, in limited studies, islet pathology. We sought evidence for different immunological phenotypes using two approaches. First, we defined blood autoimmune res...

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Detalhes bibliográficos
Main Authors: Arif, Sefina, Leete, Pia, Nguyen, Vy, Marks, Katherine, Nor, Nurhanani Mohamed, Estorninho, Megan, Kronenberg-Versteeg, Deborah, Bingley, Polly J., Todd, John A., Guy, Catherine, Dunger, David B., Powrie, Jake, Willcox, Abby, Foulis, Alan K., Richardson, Sarah J., de Rinaldis, Emanuele, Morgan, Noel G., Lorenc, Anna, Peakman, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207393/
https://ncbi.nlm.nih.gov/pubmed/24939426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0365
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