Chronic Treatment with Novel Brain-Penetrating Selective NOP Receptor Agonist MT-7716 Reduces Alcohol Drinking and Seeking in the Rat

Since its discovery, the nociceptin/orphanin FQ (N/OFQ)-NOP receptor system has been extensively investigated as a promising target to treat alcoholism. Encouraging results obtained with the endogenous ligand N/OFQ stimulated research towards the development of novel brain-penetrating NOP receptor a...

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Detalhes bibliográficos
Main Authors: Ciccocioppo, Roberto, Stopponi, Serena, Economidou, Daina, Kuriyama, Makoto, Kinoshita, Hiroshi, Heilig, Markus, Roberto, Marisa, Weiss, Friedbert, Teshima, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207340/
https://ncbi.nlm.nih.gov/pubmed/24863033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.113
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