Sex Differences in COMT Polymorphism Effects on Prefrontal Inhibitory Control in Adolescence

Catecholamine-0-methyl-transferase (COMT) gene variation effects on prefrontal blood oxygenation-level-dependent (BOLD) activation are robust; however, despite observations that COMT is estrogenically catabolized, sex differences in its prefrontal repercussions remain unclear. Here, in a large sampl...

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Autors principals: White, Thomas P, Loth, Eva, Rubia, Katya, Krabbendam, Lydia, Whelan, Robert, Banaschewski, Tobias, Barker, Gareth J, Bokde, Arun LW, Büchel, Christian, Conrod, Patricia, Fauth-Bühler, Mira, Flor, Herta, Frouin, Vincent, Gallinat, Jürgen, Garavan, Hugh, Gowland, Penny, Heinz, Andreas, Ittermann, Bernd, Lawrence, Claire, Mann, Karl, Paillère, Marie-Laure, Nees, Frauke, Paus, Tomas, Pausova, Zdenka, Rietschel, Marcella, Robbins, Trevor, Smolka, Michael N, Shergill, Sukhwinder S, Schumann, Gunter
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207335/
https://ncbi.nlm.nih.gov/pubmed/24820538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.107
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