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Molecular imaging of Cathepsin E-positive tumors in mice using a novel protease-activatable fluorescent probe

The purpose of this study is to demonstrate the ability of imaging Cathepsin E (Cath E) positive tumors in living animals through selective targeting of Cath E proteolytic activity using a sensitive molecular imaging agent. Methods: a peptide-based Cath E imaging probe and a control probe were synth...

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Main Authors: Abd-Elgaliel, Wael R., Cruz-Monserrate, Zobeida, Logsdon, Craig D., Tung, Ching-Hsuan
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207267/
https://ncbi.nlm.nih.gov/pubmed/21935563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1mb05215b
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