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The somatotropic axis and aging: Mechanisms and persistent questions about practical implications
Reduced somatotropic (GH/IGF-1) signaling delays aging and extends longevity in laboratory mice. However, it is unclear whether the physiological decrease of GH and IGF-1 levels with age represents a symptom of declining neuroendocrine function, a cause of age-related alterations in body composition...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4207209/ https://ncbi.nlm.nih.gov/pubmed/19371777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2009.04.001 |
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