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Pathological Role for Exocytotic Glutamate Release from Astrocytes in Hepatic Encephalopathy

Liver failure can lead to generalized hyperammonemia, which is thought to be the underlying cause of hepatic encephalopathy. This neuropsychiatric syndrome is accompanied by functional changes of astrocytes. These glial cells enter ammonia-induced self-amplifying cycle characterized by brain oedema,...

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Détails bibliographiques
Auteurs principaux: Montana, Vedrana, Verkhratsky, Alexei, Parpura, Vladimir
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207072/
https://ncbi.nlm.nih.gov/pubmed/25342940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X12666140903094700
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