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Evidence HDAC9 genetic variant associated with ischaemic stroke increases risk via promoting carotid atherosclerosis

BACKGROUND AND PURPOSE: A novel association between a single nucleotide polymorphism (SNP) on chromosome 7p21.1 and large vessel ischaemic stroke, was recently identified. The most likely underlying gene is histone deacetylase 9 (HDAC9). The mechanism by which HDAC9 increases stroke risk is not clea...

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Detalhes bibliográficos
Main Authors: Markus, Hugh S, Mäkelä, Kari-Matti, Bevan, Steve, Raitoharju, Emma, Oksala, Niku, Bis, Joshua C., O’Donnell, Chris, Hainsworth, Atticus, Lehtimäki, Terho
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206941/
https://ncbi.nlm.nih.gov/pubmed/23449258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.000217
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