Activation of autophagy in photoreceptor necroptosis after experimental retinal detachment

AIM: To investigate whether photoreceptor necroptosis induced by z-VAD-FMK (pan caspase inhibitor) was involved the activation of autophagy and whether Necrostatin-1, a specific necroptosis inhibitor, could inhibit this induction of autophagy after experimental retinal detachment. METHODS: Experimen...

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Autores principales: Dong, Kai, Zhu, Zi-Cheng, Wang, Feng-Hua, Ke, Gen-Jie, Yu, Zhang, Xu, Xun
Formato: Artigo
Lenguaje:Inglês
Publicado: International Journal of Ophthalmology Press 2014
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206874/
https://ncbi.nlm.nih.gov/pubmed/25349786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2014.05.01
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