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Evaluation of ultrahigh-performance liquid chromatography columns for the analysis of unmodified and antisense oligonucleotides

Ultrahigh-performance liquid chromatography has been used for the separation and analysis of unmodified and modified antisense oligonucleotides. For this reason, we tested various columns of low particle sizes in our analysis of unmodified and phosphorothioate oligonucleotides. The influence of both...

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Detalhes bibliográficos
Main Authors: Studzińska, Sylwia, Buszewski, Bogusław
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206774/
https://ncbi.nlm.nih.gov/pubmed/24939137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-014-7959-5
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