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Genetic and structural identification of an O-acyltransferase gene (oacC) responsible for the 3/4-O-acetylation on rhamnose III in Shigella flexneri serotype 6

BACKGROUND: O-antigen (O-polysaccharide) of the lipopolysaccharide is a highly variable cell component of the outer membrane in Shigella flexneri. It defines the serospecificity and plays an important role in the pathogenesis of shigellosis. There are two distinct O-antigen forms for the 19 serotype...

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Autores principales: Knirel, Yuriy A, Wang, Jianping, Luo, Xia, Senchenkova, Sofya N, Lan, Ruiting, Shpirt, Anna M, Du, Pengcheng, Shashkov, Alexander S, Zhang, Nan, Xu, Jianguo, Sun, Qiangzheng
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206707/
https://ncbi.nlm.nih.gov/pubmed/25327486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-014-0266-7
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