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Analytic power and sample size calculation for the genotypic transmission/disequilibrium test in case-parent trio studies

Case-parent trio studies considering genotype data from children affected by a disease and from their parents are frequently used to detect single nucleotide polymorphisms (SNPs) associated with disease. The most popular statistical tests in this study design are transmission/disequlibrium tests (TD...

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書誌詳細
主要な著者: Neumann, Christoph, Taub, Margaret A., Younkin, Samuel G., Beaty, Terri H., Ruczinski, Ingo, Schwender, Holger
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206700/
https://ncbi.nlm.nih.gov/pubmed/25123830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201300148
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