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Isoniazid in autoimmunity: a trigger for multiple sclerosis?
Isoniazid (INH) is a prodrug activated by the mycobacterial enzyme KatG, a multifunctional catalase peroxidase. KatG converts INH to reactive antimycobacterial species. For decades, an association between INH and drug-induced lupus erythematosus has been recognized. We present the case of a patient...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
SAGE Publications
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4206619/ https://ncbi.nlm.nih.gov/pubmed/25342979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756285614540361 |
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