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Endocrine and neurobehavioral abnormalities induced by propofol administered to neonatal rats

BACKGROUND: We studied whether neonatal propofol anesthesia affects development of the endocrine and neural systems. METHODS: Sprague-Dawley rats were anesthetized using intraperitoneal propofol for 5 h on postnatal days (P) 4, 5, or 6. Pups that received either saline or intralipid, but not those i...

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Detalhes bibliográficos
Main Authors: Tan, Sijie, Xu, Changqing, Zhu, Wanting, Willis, Jesse, Seubert, Christoph N., Gravenstein, Nikolaus, Sumners, Colin, Martynyuk, Anatoly E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206572/
https://ncbi.nlm.nih.gov/pubmed/24992523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000366
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