Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1-containing membranes

Autophagy is a lysosomal degradative pathway that has diverse physiological functions and plays crucial roles in several viral infections. Here we examine the role of autophagy in the life cycle of JEV, a neurotropic flavivirus. JEV infection leads to induction of autophagy in several cell types. JE...

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Detalhes bibliográficos
Main Authors: Sharma, Manish, Bhattacharyya, Sankar, Nain, Minu, Kaur, Manpreet, Sood, Vikas, Gupta, Vishal, Khasa, Renu, Abdin, Malik Z, Vrati, Sudhanshu, Kalia, Manjula
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206540/
https://ncbi.nlm.nih.gov/pubmed/25046112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.29455
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