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Pixel-based absorption correction for dual-tracer fluorescence imaging of receptor binding potential

Ratiometric approaches to quantifying molecular concentrations have been used for decades in microscopy, but have rarely been exploited in vivo until recently. One dual-tracer approach can utilize an untargeted reference tracer to account for non-specific uptake of a receptor-targeted tracer, and ul...

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Detalhes bibliográficos
Main Authors: Kanick, Stephen C., Tichauer, Kenneth M., Gunn, Jason, Samkoe, Kimberley S., Pogue, Brian W.
Formato: Artigo
Idioma:Inglês
Publicado em: Optical Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206301/
https://ncbi.nlm.nih.gov/pubmed/25360349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.5.003280
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