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Quantitative Cross-Species Extrapolation between Humans and Fish: The Case of the Anti-Depressant Fluoxetine

Fish are an important model for the pharmacological and toxicological characterization of human pharmaceuticals in drug discovery, drug safety assessment and environmental toxicology. However, do fish respond to pharmaceuticals as humans do? To address this question, we provide a novel quantitative...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Margiotta-Casaluci, Luigi, Owen, Stewart F., Cumming, Rob I., de Polo, Anna, Winter, Matthew J., Panter, Grace H., Rand-Weaver, Mariann, Sumpter, John P.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2014
الموضوعات:
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206295/
https://ncbi.nlm.nih.gov/pubmed/25338069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110467
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