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Combining Physicochemical and Evolutionary Information for Protein Contact Prediction

We introduce a novel contact prediction method that achieves high prediction accuracy by combining evolutionary and physicochemical information about native contacts. We obtain evolutionary information from multiple-sequence alignments and physicochemical information from predicted ab initio protein...

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Détails bibliographiques
Auteurs principaux: Schneider, Michael, Brock, Oliver
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206277/
https://ncbi.nlm.nih.gov/pubmed/25338092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108438
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