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Exogenous and endogenous hyaluronic acid reduces HIV infection of CD4(+) T cells

Preventing mucosal transmission of HIV is critical to halting the HIV epidemic. Novel approaches to preventing mucosal transmission are needed. Hyaluronic acid (HA) is a major extracellular component of mucosa and the primary ligand for the cell surface receptor CD44. CD44 enhances HIV infection of...

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Bibliografiske detaljer
Main Authors: Li, Peilin, Fujimoto, Katsuya, Bourguingnon, Lilly, Yukl, Steven, Deeks, Steven, Wong, Joseph K
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205896/
https://ncbi.nlm.nih.gov/pubmed/24957217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2014.50
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