MAGI-2 scaffold protein is critical for kidney barrier function

MAGUK Inverted 2 (MAGI-2) is a PTEN-interacting scaffold protein implicated in cancer on the basis of rare, recurrent genomic translocations and deletions in various tumors. In the renal glomerulus, MAGI-2 is exclusively expressed in podocytes, specialized cells forming part of the glomerular filter...

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Bibliographische Detailangaben
Hauptverfasser: Balbas, Minna D., Burgess, Michael R., Murali, Rajmohan, Wongvipat, John, Skaggs, Brian J., Mundel, Peter, Weins, Astrid, Sawyers, Charles L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205655/
https://ncbi.nlm.nih.gov/pubmed/25271328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417297111
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