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Transmembrane domain of surface-exposed outer membrane lipoprotein RcsF is threaded through the lumen of β-barrel proteins

RcsF (regulator of capsule synthesis) is an outer membrane (OM) lipoprotein that functions to sense defects such as changes in LPS. However, LPS is found in the outer leaflet, and RcsF was thought to be tethered to the inner leaflet by its lipidated N terminus, raising the question of how it monitor...

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Bibliographic Details
Main Authors: Konovalova, Anna, Perlman, David H., Cowles, Charles E., Silhavy, Thomas J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205638/
https://ncbi.nlm.nih.gov/pubmed/25267629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417138111
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