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Polarity mechanisms such as contact inhibition of locomotion regulate persistent rotational motion of mammalian cells on micropatterns

Pairs of endothelial cells on adhesive micropatterns rotate persistently, but pairs of fibroblasts do not; coherent rotation is present in normal mammary acini and kidney cells but absent in cancerous cells. Why? To answer this question, we develop a computational model of pairs of mammalian cells o...

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Detalhes bibliográficos
Main Authors: Camley, Brian A., Zhang, Yunsong, Zhao, Yanxiang, Li, Bo, Ben-Jacob, Eshel, Levine, Herbert, Rappel, Wouter-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205601/
https://ncbi.nlm.nih.gov/pubmed/25258412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414498111
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