Enhanced production of L-sorbose from D-sorbitol by improving the mRNA abundance of sorbitol dehydrogenase in Gluconobacter oxydans WSH-003

BACKGROUND: Production of L-sorbose from D-sorbitol by Gluconobacter oxydans is the first step to produce L-ascorbic acid on industrial scale. The sldhAB gene, which encodes the sorbitol dehydrogenase (SLDH), was overexpressed in an industrial strain G. oxydans WSH-003 with a strong promoter, P(tufB...

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Autors principals: Xu, Sha, Wang, Xiaobei, Du, Guocheng, Zhou, Jingwen, Chen, Jian
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205284/
https://ncbi.nlm.nih.gov/pubmed/25323199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-014-0146-8
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