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Cellular Zinc Levels are Modulated by Trpml1-Tmem163 Interaction
Mucolipidosis type IV (MLIV) is caused by loss of function mutations in the TRPML1 ion channel. We previously reported that tissue zinc levels in MLIV were abnormally elevated; however, the mechanism behind this pathologic accumulation remains unknown. Here, we identify transmembrane (TMEM)-163 prot...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4205267/ https://ncbi.nlm.nih.gov/pubmed/25130899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12205 |
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