Measurement and Characterization of Superoxide Generation from Xanthine Dehydrogenase: A Redox-Regulated Pathway of Radical Generation in Ischemic Tissues

[Image: see text] The enzyme xanthine oxidoreductase (XOR) is an important source of oxygen free radicals and related postischemic injury. Xanthine dehydrogenase (XDH), the major form of XOR in tissues, can be converted to xanthine oxidase (XO) by oxidation of sulfhydryl residues or by proteolysis....

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Hlavní autoři: Lee, Masaichi-Chang-il, Velayutham, Murugesan, Komatsu, Tomoko, Hille, Russ, Zweier, Jay L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204892/
https://ncbi.nlm.nih.gov/pubmed/25243829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500582r
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