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Neuropeptide precursor VGF is genetically associated with social anhedonia and underrepresented in the brain of major mental illness: its downregulation by DISC1

In a large Scottish pedigree, disruption of the gene coding for DISC1 clearly segregates with major depression, schizophrenia and related mental conditions. Thus, study of DISC1 may provide a clue to understand the biology of major mental illness. A neuropeptide precursor VGF has potent antidepressa...

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Detalhes bibliográficos
Main Authors: Ramos, Adriana, Rodríguez-Seoane, Carmen, Rosa, Isaac, Trossbach, Svenja V., Ortega-Alonso, Alfredo, Tomppo, Liisa, Ekelund, Jesper, Veijola, Juha, Järvelin, Marjo-Riitta, Alonso, Jana, Veiga, Sonia, Sawa, Akira, Hennah, William, García, Ángel, Korth, Carsten, Requena, Jesús R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204764/
https://ncbi.nlm.nih.gov/pubmed/24934694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu303
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