The connexin43 mimetic peptide Gap19 inhibits hemichannels without altering gap junctional communication in astrocytes

In the brain, astrocytes represent the cellular population that expresses the highest amount of connexins (Cxs). This family of membrane proteins is the molecular constituent of gap junction channels and hemichannels that provide pathways for direct cytoplasm-to-cytoplasm and inside-out exchange, re...

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Detalhes bibliográficos
Main Authors: Abudara, Verónica, Bechberger, John, Freitas-Andrade, Moises, De Bock, Marijke, Wang, Nan, Bultynck, Geert, Naus, Christian C., Leybaert, Luc, Giaume, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204617/
https://ncbi.nlm.nih.gov/pubmed/25374505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00306
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