Lentiviral Mediating Genetic Engineered Mesenchymal Stem Cells for Releasing IL-27 as a Gene Therapy Approach for Autoimmune Diseases

OBJECTIVE: Autoimmune diseases precede a complex dysregulation of the immune system. T helper17 (Th17) and interleukin (IL)-17 have central roles in initiation of inflammation and subsequent autoimmune diseases. IL-27 significantly controls autoimmune diseases by Th17 and IL-17 suppression. In the p...

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Main Authors: Hajizadeh-Sikaroodi, Shohreh, Hosseini, Ahmad, Fallah, Ali, Estiri, Hajar, Noormohammadi, Zahra, Salehi, Mohammad, Ghaderian, Sayyed Mohammad Hossein, Akhavan Niaki, Haleh, Soleimani, Masoud, Kazemi, Bahram
Formato: Artigo
Idioma:Inglês
Publicado em: Royan Institute 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204184/
https://ncbi.nlm.nih.gov/pubmed/24611150
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