Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25

The genetic contributions to breast cancer development among Latinas are not well understood. Here we carry out a genome-wide association study of breast cancer in Latinas and identify a genome-wide significant risk variant, located 5′ of the Estrogen Receptor 1 gene (ESR1; 6q25 region). The minor a...

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Main Authors: Fejerman, Laura, Ahmadiyeh, Nasim, Hu, Donglei, Huntsman, Scott, Beckman, Kenneth B., Caswell, Jennifer L., Tsung, Karen, John, Esther M., Torres-Mejia, Gabriela, Carvajal-Carmona, Luis, Echeverry, María Magdalena, Tuazon, Anna Marie D., Ramirez, Carolina, Gignoux, Christopher R., Eng, Celeste, Gonzalez-Burchard, Esteban, Henderson, Brian, Marchand, Loic Le, Kooperberg, Charles, Hou, Lifang, Agalliu, Ilir, Kraft, Peter, Lindström, Sara, Perez-Stable, Eliseo J., Haiman, Christopher A., Ziv, Elad
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204111/
https://ncbi.nlm.nih.gov/pubmed/25327703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6260
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