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Programmable cells: Interfacing natural and engineered gene networks

Novel cellular behaviors and characteristics can be obtained by coupling engineered gene networks to the cell's natural regulatory circuitry through appropriately designed input and output interfaces. Here, we demonstrate how an engineered genetic circuit can be used to construct cells that res...

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Detalhes bibliográficos
Main Authors: Kobayashi, Hideki, Kærn, Mads, Araki, Michihiro, Chung, Kristy, Gardner, Timothy S., Cantor, Charles R., Collins, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC420408/
https://ncbi.nlm.nih.gov/pubmed/15159530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402940101
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