Improvement in the stability and functionality of Nicotiana tabacum produced recombinant TRAIL through employment of endoplasmic reticulum expression and ascorbate buffer mediated extraction strategies

Introduction: In order to employ Nicotiana tabacum cells as a profitable natural bioreactor for production of bio-functional "Soluble human TRAIL" (ShTRAIL), endoplasmic reticulum (ER) targeted expression and innovative extraction procedures were exploited. Methods: At first, the ShTRAIL e...

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Detalhes bibliográficos
Main Authors: Heidari, Hamid Reza, Bandehpour, Mojgan, Vahidi, Hossein, Barar, Jaleh, Kazemi, Bahram, Naderi-Manesh, Hossein
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4204037/
https://ncbi.nlm.nih.gov/pubmed/25337465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/bi.2014.005
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