Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid–lysophosphatidic acid receptor 1 cascade

INTRODUCTION: Lysophosphatidic acid (LPA) is a bioactive lipid that binds to G protein–coupled receptors (LPA(1–6)). Recently, we reported that abrogation of LPA receptor 1 (LPA(1)) ameliorated murine collagen-induced arthritis, probably via inhibition of inflammatory cell migration, Th17 differenti...

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Detalhes bibliográficos
Main Authors: Miyabe, Yoshishige, Miyabe, Chie, Iwai, Yoshiko, Yokoyama, Waka, Sekine, Chiyoko, Sugimoto, Kazutaka, Harigai, Masayoshi, Miyasaka, Masayuki, Miyasaka, Nobuyuki, Nanki, Toshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203966/
https://ncbi.nlm.nih.gov/pubmed/25273676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-014-0461-9
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