Molecular characterisation of isogenic taxane resistant cell lines identify novel drivers of drug resistance

BACKGROUND: Taxanes such as paclitaxel and docetaxel are used successfully to treat breast cancer, usually in combination with other agents. They interfere with microtubules causing cell cycle arrest; however, the mechanisms underlying the clinical effects of taxanes are yet to be fully elucidated....

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Autori principali: Kenicer, Juliet, Spears, Melanie, Lyttle, Nicola, Taylor, Karen J, Liao, Linda, Cunningham, Carrie A, Lambros, Maryou, MacKay, Alan, Yao, Cindy, Reis-Filho, Jorge, Bartlett, John MS
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203938/
https://ncbi.nlm.nih.gov/pubmed/25312014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-762
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