Persistent Lyme Empiric Antibiotic Study Europe (PLEASE) - design of a randomized controlled trial of prolonged antibiotic treatment in patients with persistent symptoms attributed to Lyme borreliosis

BACKGROUND: Lyme borreliosis, a potentially severe tick-borne infection caused by Borrelia burgdorferi, can cause multi-system inflammatory disease. The incidence has been increasing, as has the number of patients with persistent symptoms attributed to Borrelia. These symptoms, also referred to as p...

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Detalhes bibliográficos
Main Authors: Berende, Anneleen, ter Hofstede, Hadewych JM, Donders, A Rogier T, van Middendorp, Henriët, Kessels, Roy PC, Adang, Eddy MM, Vos, Fidel J, Evers, Andrea WM, Kullberg, Bart Jan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203907/
https://ncbi.nlm.nih.gov/pubmed/25318999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-014-0543-y
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