Crystal structure of LeuA from Mycobacterium tuberculosis, a key enzyme in leucine biosynthesis
The leucine biosynthetic pathway is essential for the growth of Mycobacterium tuberculosis and is a potential target for the design of new anti-tuberculosis drugs. The crystal structure of α-isopropylmalate synthase, which catalyzes the first committed step in this pathway, has been determined by mu...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420388/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15159544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0400820101 |
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