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Collaboration of homologous recombination and nonhomologous end-joining factors for the survival and integrity of mice and cells

Homologous recombination (HR) and nonhomologous end-joining (NHEJ) are mechanistically distinct DNA repair pathways that contribute substantially to double-strand break (DSB) repair in mammalian cells. We have combined mutations in factors from both repair pathways, the HR protein Rad54 and the DNA-...

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Published in:Genes Dev
Main Authors: Couëdel, Chrystelle, Mills, Kevin D., Marco, Barchi, Shen, Lingbo, Olshen, Adam, Johnson, Roger D., Nussenzweig, André, Essers, Jeroen, Kanaar, Roland, Li, Gloria C., Alt, Frederick W., Jasin, Maria
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2004
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Research Papers
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15175261/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1209204
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