A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

Histone lysine methylation is a central modification to mark functionally distinct chromatin regions. In particular, H3-K9 trimethylation has emerged as a hallmark of pericentric heterochromatin in mammals. Here we show that H4-K20 trimethylation is also focally enriched at pericentric heterochromat...

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Pubblicato in:	Genes Dev
Autori principali:	Schotta, Gunnar, Lachner, Monika, Sarma, Kavitha, Ebert, Anja, Sengupta, Roopsha, Reuter, Gunter, Reinberg, Danny, Jenuwein, Thomas
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2004
Soggetti:	Research Papers
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC420351/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15145825/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.300704
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