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Depletion of T Regulatory Cells Promotes Natural Killer Cell-Mediated Cardiac Allograft Vasculopathy

BACKGROUND: A role for NK cells in cardiac allograft vasculopathy (CAV) was suggested by our earlier observation that CAV arises even in the absence of detectable anti-donor T or B cell reactivity in parental to F1 mouse heart grafts. However, prevention of CAV in this setting required the depletion...

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Detalhes bibliográficos
Main Authors: Hirohashi, Tsutomu, Chase, Catharine M., DellaPelle, Patricia, Sebastian, Divya, Farkesh, Evan, Colvin, Robert B., Russell, Paul S., Alessandrini, Alessandro, Madsen, Joren C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203423/
https://ncbi.nlm.nih.gov/pubmed/25321164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000000329
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