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Calorie restriction in mice overexpressing UCP3: evidence that prior mitochondrial uncoupling alters response
Calorie restriction (CR) without malnutrition is the only intervention to consistently increase lifespan in all species tested, and lower age-related pathologies in mammals including humans. It has been suggested that uncoupling of mitochondrial oxidative phosphorylation, using chemical uncouplers,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4203376/ https://ncbi.nlm.nih.gov/pubmed/22406134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2012.02.008 |
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