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Mutagenicity of the peroxisome proliferators clofibrate, Wyeth 14,643 and di-2-ethylhexyl phthalate in the lacZ plasmid-based transgenic mouse mutation assay

BACKGROUND: Peroxisome proliferators are considered rodent carcinogens that are putative human non-carcinogens based on the presumed absence of direct genetic toxicity in rodent and human cells and the resistance of human cells to the induction of peroxisomes by peroxisome proliferators. The highly...

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Détails bibliographiques
Auteur principal: Boerrigter, Michaël ETI
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC420255/
https://ncbi.nlm.nih.gov/pubmed/15128457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-3-7
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