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Ionizing radiation affects the expression of Toll-like receptors 2 and 4 in human monocytic cells through c-Jun N-terminal kinase activation

Pattern recognition receptors recognize pathogen-associated molecular patterns. Among these, Toll-like receptors (TLRs) have well-characterized roles in antibacterial and antiviral immunity. In the present study, the effects of ionizing radiation on the expression of TLRs and cellular responses to l...

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Bibliographic Details
Main Authors: Yoshino, Hironori, Chiba, Kanae, Saitoh, Takahiro, Kashiwakura, Ikuo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202298/
https://ncbi.nlm.nih.gov/pubmed/24927726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rru040
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