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Design, synthesis, and application of tartaric acid derived N-spiro quaternary ammonium salts as chiral phase-transfer catalysts

A novel class of tartaric acid-derived N-spiro quaternary ammonium salts was synthesised starting from known TADDOLs. These compounds were found to catalyse the asymmetric α-alkylation of glycine Schiff bases with high enantioselectivities and in good yields.

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Detalhes bibliográficos
Main Authors: Waser, Mario, Gratzer, Katharina, Herchl, Richard, Müller, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202190/
https://ncbi.nlm.nih.gov/pubmed/22038391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1ob06573d
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