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MicroRNA-mediated down-regulation of NKG2D ligands contributes to glioma immune escape

Malignant gliomas are intrinsic brain tumors with a dismal prognosis. They are well-adapted to hypoxic conditions and poorly immunogenic. NKG2D is one of the major activating receptors of natural killer (NK) cells and binds to several ligands (NKG2DL). Here we evaluated the impact of miRNA on the ex...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Codo, Paula, Weller, Michael, Meister, Gunter, Szabo, Emese, Steinle, Alexander, Wolter, Marietta, Reifenberger, Guido, Roth, Patrick
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202151/
https://ncbi.nlm.nih.gov/pubmed/25277195
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