A Plasmodium falciparum PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surface

Uniquely among malaria parasites, Plasmodium falciparum-infected erythrocytes (iRBCs) develop membrane protrusions, known as knobs, where the parasite adhesion receptor P. falciparum erythrocyte membrane protein 1 (PfEMP1) clusters. Knob formation and the associated iRBC adherence to host endotheliu...

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Detalhes bibliográficos
Main Authors: Oberli, Alexander, Slater, Leanne M., Cutts, Erin, Brand, Françoise, Mundwiler-Pachlatko, Esther, Rusch, Sebastian, Masik, Martin F. G., Erat, Michèle C., Beck, Hans-Peter, Vakonakis, Ioannis
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202109/
https://ncbi.nlm.nih.gov/pubmed/24983468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-256057
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