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Roles of transforming growth factor-β1 and OB-cadherin in porcine cardiac valve myofibroblast differentiation

Calcific aortic stenosis is a common disease, and some of its early causes are the activation and differentiation of resident fibroblasts to myofibroblasts in response to transforming growth factor β1 (TGF-β1). The aim of this study was to understand how TGF-β1 and its downstream effector, OB-cadher...

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Detalhes bibliográficos
Main Authors: Wang, Huan, Leinwand, Leslie A., Anseth, Kristi S.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202096/
https://ncbi.nlm.nih.gov/pubmed/25008089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-254623
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