Dexmedetomidine-induced Contraction Involves Phosphorylation of Caldesmon by JNK in Endothelium-denuded Rat Aortas

Caldesmon, an inhibitory actin binding protein, binds to actin and inhibits actin-myosin interactions, whereas caldesmon phosphorylation reverses the inhibitory effect of caldesmon on actin-myosin interactions, potentially leading to enhanced contraction. The goal of this study was to investigate th...

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Autores principales: Baik, Jiseok, Ok, Seong-Ho, Cho, Hyunhoo, Yu, Jongsun, Kim, Woochan, Nam, In-Koo, Choi, Mun-Jeoung, Lee, Heon-Keun, Sohn, Ju-Tae
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202027/
https://ncbi.nlm.nih.gov/pubmed/25332685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.9797
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