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Small Molecules Targeting c-Myc Oncogene: Promising Anti-Cancer Therapeutics

The nuclear transcription factor c-Myc is a member of the Myc gene family with multiple functions and located on band q24.1 of chromosome 8. The c-Myc gene is activated by chromosomal translocation, rearrangement, and amplification. Its encoded protein transduces intracellular signals to the nucleus...

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Autors principals: Chen, Bing-Jia, Wu, Yan-Ling, Tanaka, Yoshimasa, Zhang, Wen
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202025/
https://ncbi.nlm.nih.gov/pubmed/25332683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.10190
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