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CD44-mediated Adhesion to Hyaluronic Acid Contributes to Mechanosensing and Invasive Motility
The high molecular weight glycosaminoglycan, hyaluronic acid (HA), makes up a significant portion of the brain extracellular matrix (ECM). Glioblastoma multiforme (GBM), a highly invasive brain tumor, is associated with aberrant HA secretion, tissue stiffening, and overexpression of the HA receptor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201971/ https://ncbi.nlm.nih.gov/pubmed/24962319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0629 |
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