Internalization by Multiple Endocytic Pathways and Lysosomal Processing Impact Maspin-based Therapeutics

Patients with metastatic disease face high rates of mortality with a paucity of therapeutic options. Protein-based therapeutics provides advantages over traditional chemotherapy through increased specificity, decreased immune responses and more direct means of delivery. However, development is often...

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Autori principali: Bodenstine, Thomas M., Seftor, Richard E. B., Seftor, Elisabeth A., Khalkhali-Ellis, Zhila, Samii, Nicole A., Monarrez, J. Cesar, Chandler, Grace S., Pemberton, Philip A., Hendrix, Mary J. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201961/
https://ncbi.nlm.nih.gov/pubmed/25256709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0067
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